12 Over-The-Counter Appetite Suppressants Reviewed

12 Over-The-Counter Appetite Suppressants Reviewed

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Over-The-Counter Appetite Suppressants Reviewed

Conjugated Linoleic Acid (CLA)

A fatty acid claimed to reduce fat storage and curb hunger. Studies show mixed results on weight loss effectiveness.

Bitter Orange (Synephrine)

Contains synephrine, a stimulant similar to ephedrine. May increase metabolism but carries cardiovascular risks for some users.

Garcinia Cambogia

Extract from Southeast Asian fruit; inhibits fat production and promotes satiety. Clinical evidence lacks consistency in real-world results.

Glucomannan

A soluble fiber derived from konjac root. Forms gel in the stomach, prolonging fullness. Often used as a dietary supplement with minimal side effects.

Hoodia Gordonii

South African cactus extract historically used by indigenous tribes. Limited human trials show inconsistent suppression of appetite.

Green Coffee Bean Extract

Rich in chlorogenic acid, which may slow carbohydrate absorption. Some studies suggest modest weight loss benefits at higher doses.

Guarana

Natural caffeine source boosting energy and focus, indirectly reducing cravings. Effects similar to coffee but with added antioxidants.

Acacia Fiber

Soluble fiber supplement that expands in the stomach, inducing early fullness. Often used for digestive health alongside appetite control.

Saffron Extract

Pigment from saffron crocus shown to reduce hunger and improve mood. Studies highlight psychological effects over direct physiological suppression.

Guar Gum

A fiber thickening agent that creates viscosity in the gut, enhancing satiety. Commonly added to foods for texture and weight management support.

Forskolin

Dervied from the Coleus forskohlii plant; stimulates enzymes affecting metabolism. Research on appetite suppression remains limited and inconclusive.

Chromium Picolinate

Micronutrient that enhances insulin sensitivity, potentially reducing sugar cravings. Minimal direct evidence for standalone weight loss benefits.

The Bottom Line

No single OTC appetite suppressant guarantees significant results. Efficacy varies by individual and product quality. Pair with diet and exercise for best outcomes.

How we reviewed this article:

Products were evaluated based on clinical trial data, safety profiles, and user reviews. Focus placed on ingredients with published research supporting their mechanisms of action.